Neurosurgery
Outline
"Primary research themes of our department of neurosurgery are surgical strategies, pathophysiological analyses, and the clinicopathological diagnoses of spinal disorders, cerebrovascular diseases, brain tumors (especially hypothalamic-pituitary tumors), and congenital anomalies of the central nervous system in children.
- Spinal disorders: Through the use of experimental animal models, we aim to elucidate the mechanisms involved in tissue destruction and degenerative progression in acute spinal cord injury, and in the pathogenesis of compressive myelopathy, especially in chronically compressed white matter of the spinal cord.
- Cerebrovascular diseases: We investigate neurodegeneration and neuronal death in the peri-infarct and remote areas in experimental stroke models, and selective neuronal death and apoptosis in transient global ischemic models.
- Brain tumors: Our research involves clinicopathological studies of hypothalamic and pituitary tumors as well as molecular biological analyses. Our pathological analyses cover the mechanisms of brain tumor-induced headaches, radiological evaluation (imaging diagnosis) of central diabetes insipidus, symptoms associated with pressure in the sella turcica, and the mechanisms involved in edema formation caused by craniopharyngioma."
e-mail: neurosur@kanazawa-med.ac.jp
Faculty
Professor and Chair
Professor (Adjunct)
Associate Professor
OGIWARA Toshihiro
Senior Assistant Professor
Assistant Professor
Assistant Professor
TAKATA Sho
Research Achievements
- Takata S, Sakata-Haga H, Shimada H, Tsukada T, Sakai D, Shoji H, Tomosugi M, Nakamura Y, Ishigaki Y, Iizuka H, Hayashi Y, Hatta T: LIF-IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum, International Journal of Molecular Sciences, 30;23(21):13199, 2022.
- Shojima H, Hayashi Y, Tamase A, Takata S, Iizuka H: Traumatic retroclival epidural hematoma associated with reversible ipsilateral internal carotid artery stenosis, Child's Nervous System, 38(2):485-489, 2022.
- Tsuyoshi Tsukada, Hiroki Shimada, Hiromi Sakata-Haga, Hiroki Shoji, Hideaki Iizuka, Toshihisa Hatta: Decidual cells are the initial target of polyriboinosinic-polyribocytidylic acid in a mouse model of maternal viral infection, Biochemistry and biophysics reports, 26: 100958-100958, 2021.
- Takata S, Tamase A, Hayashi Y, Tachibana O, Sato K, Iizuka H: Pediatric meningioma with rhabdoid features developed at the site of skull fracture:illustrative case, J Neurosurg. Case Lessons, 2: 14; CASE21107, 2021.
- Sho Takata, Akira Tamase, Yasuhiko Hayashi, Kazushi Anzawa, Akihiro Shioya c, Yoshitsugu Iinuma, Hideaki Iizuka, Ruptured fungal aneurysm of the peripheral middle cerebral artery caused by Lomentospora infection: A case report and literature review. Interdisciplinary Neurosurgery, Volume 21, September 2020, 100743
External Research Funding
- Tachibana O. 2010～2012 The Japanese Grant-in-Aid for Scientific Research (C).
Contribution of the inflammatory cytokines and aquaporines in the progression of symptomatic Rathke’s cyst.