Division of General Education - Natural Sciences
Chemistry
Contact Information
TEL: 076-286-2211
e-mail: 驳别苍-别诲耻【蔼】办补苍补锄补飞补-尘别诲.补肠.箩辫
e-mail: 驳别苍-别诲耻【蔼】办补苍补锄补飞补-尘别诲.补肠.箩辫
Faculty
Senior Assistant Professor
Research Achievements
- Ota T., Maeda M., Okamoto M., Tatsuka M. Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs. BMC Systems Biology. 9:3, 2015
- M.Maeda, M.Murakami, T.Takegami, T.Ota. Promotion or suppression of experimental metastasis of B16 melanoma cells. Toxicol. Appl. Pharmacol. 229:232-238 2008
- T. Ota, M. Maeda, M. Murakami, T. Takegami, S. Suto, M. Tatsuka, Activation of Rac1 by Rho-guanine nucleotide dissociation inhibitor-β with defective isoprenyl-binding pocket. Cell Biol. Int., 31:92-96, 2007
- T. Ota, M. Maeda, S. Suto, Xinwen Zhou, M. Murakami, T. Takegami, M. Tatsuka, RhoGDIβ lacking the N-terminal regulatory domain suppresses metastasis by promoting anoikis in v-src transformed cells. Clin. Exp. Metastasis, 23:323-334, 2006
- T.Ota, M.Maeda, S. Sato, M. Tatsuka, LyGDI functions in cancer metastasis by anchoring Rho proteins to the cell membrane. Mol. Carcinogenesis, 39:206-220, 2004
External Research Funding
- Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science, Scientific Research C (2006, 2007) (18590706), Mechanism of metastasis inhibition by LyGDI cleaved by caspase-1
- Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science, Scientific Research C (2004, 2005) (16591368), Relationship between the membrane localization of D4GDI and the cancer progression in human colon cancer cells.
- Grant-in-Aid for Scientific Research from the Japan Society for the Promotion of Science, Scientific Research C (2001, 2002) (13671354), Investigation of the mechanism of metastasis induction by D4GDI isolated as a metastasis-inducing gene from human colon cancer cell line.