色多多视频

Departments

医学部研究室一覧のイメージ
School of Medicine - Basic Medical Science

Immunology

Outline

Welcome to our laboratory!!

In our laboratory, we are dedicated to elucidating the differentiation origin and regulatory mechanisms of dendritic cells, monocytes, and macrophages with phagocytic functions, which play central roles in immune responses. Additionally, we focus on functional analysis of mononuclear phagocytes in the onset and progression of inflammatory diseases, and strive to discover cells and molecules that could serve as molecular targets for drug development. Furthermore, we are engaged in research aimed at developing therapeutic approaches for inflammatory diseases.

Contact Information
TEL: 076-218-8121 / FAX: 076-218-8121
e-mail: serol@kanazawa-med.ac.jp

Faculty

Professor and Chair

Assistant Professor

KOIZUMI Shinichi

Assistant

Adjunct Lecturer

Secretary

NAKAMURA Hiromi

Research Achievements

Matsuba S, Ura H, Saito F, Ogasawara C, Shimodaira S, Niida Y, Onai N. An optimized cocktail of small molecule inhibitors promotes the maturation of dendritic cells in GM-CSF mouse bone marrow culture. Front. Immunol., 2023, 13;14:1264609. doi: 10.3389/fimmu.2023.1264609.

Yang X, Yabe-Wada T, Han J, Saito F, Ogasawara C, Yamada S, *Onai N. PCBP1 acts as a regulator of CCL2 expression in macrophages to induce recruitment of monocyte-derived macrophages into the inflamed colon. Int. Immunol., 2023, doi: 10.1093/intimm/dxad003.

Kamio N, Yokota A, Tokuda Y, Ogasawara C, Nakano M, Nagao M, Tashiro K, Maekawa T, Onai N, Hirai H. A novel CD135+ subset of mouse monocytes with a distinct differentiation pathway and antigen-presenting properties. J. Immunol., 2022, 209(3):498-509.

Ohteki T, Kawamura S and Onai N. Commitment to dendritic cells and monocytes. Int. Immunol., 33:815-819, (2021).

Onai N, Asano J, Kurosaki R, Kuroda S, Ohteki T. Flexible fate commitment of E2-2high common DC progenitors implies tuning in tissue microenvironments. Int. Immunol., 29: 443-456, 2017.

External Research Funding

Links