Hepatology
Outline
In February, 2013, the Department of Hepatology became a clinical department at 色多多视频 Hospital, independent of the Department of Gastroenterology. Then in September, 2016, the Department of Hepatology was established in the School of Medicine.
In clinical practice, we treat patients with gastrointestinal disorders, especially patients with hepatobiliary and pancreatic diseases. In particular, we conduct antiviral therapy for hepatitis B and C patients, and, in collaboration with the Department of Radiology, we perform radiofrequency ablation and transcatheter arterial chemoembolization for patients with hepatocellular carcinoma. We actively employ endoscopic treatment for pancreatic cancer and biliary tract diseases such as cholelithiasis.
In research, our focus is on elucidation of the mechanisms involved in the pathogenesis of alcoholic liver diseases and non-alcoholic steatohepatitis. Presently, we are conducting research on the prevention of hepatic ischemia and reperfusion injury. In addition, we are collaborating with the Regenerative Medicine Center and Medical Research Institute on the theme of liver regeneration with hepatic stem cells.
In education, the whole department is dedicated to training students in Bedside Learning and Clinical Clerkship, giving unit lectures, and providing individual tutoring to some 6th year students as part of their preparation for the National Examination. In postgraduate medical education, we teach various procedures to the residents and also help them acquire the necessary knowledge and skills for diagnosis and treatment.
All our members are doing their best in education, treatment and research to make our department vibrant and active.
e-mail: hepatol@kanazawa-med.ac.jp
Faculty
Professor and chief
Professor Emeritus
Adjunct Professor
Associate Professor
Associate Professor
Senior Assistant Professor
Senior Assistant Professor
Senior Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
Assistant Professor
KUSUNO Satsuki
Assistant Professor
TSUMURA Takashi
Research Achievements
Inhibition of γ-glutamyltransferase ameliorates ischaemia-reoxygenation tissue damage in rats with hepatic steatosis. Ryuichi Kubota, Nobuhiko Hayashi, Kaori Kinoshita, Takashi Saito, Kazuaki Ozaki, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi, Joseph George. British Journal of Pharmacology 2020; 177: 5195-5207
Metabolism of N-nitorosodimethylamine, methylaion of macromolecules, and development of hepatic fibrosis in rodent models. Joseph George, Mutsumi Tsuchishima, Mikihiro Tsutsumi.Journal of Molecular Medicine 2020; 98 (9): 1203-1213.
Metabolism and interactions of antileprosy drugs. Joseph George. Biochemical Pharmacology 2020; 177: 113993
Recombinant thrombomodulin prevented hepatic ischemia-reperfusion injury by inhibiting high-mobility group box 1. Yuki Hirakawa, Mutsumi Tsuchishima, Atsushi Fukumura, Kaori Kinoshita, Nobuhiko Hayashi, Takashi Saito, Joseph George, Nobuyuki Toshikuni, Yoshimichi Ueda and Mikihiro Tsutsumi, European Journal of Pharmacology 2019; 863: Article number: 172681
The Combination of fatty liver and increased gamma-glutamyl transpeptidase levels as a risk factor for atherosclerotic plaque development in apparently healthy people. Kaori Kinoshita, Nobuyuki Toshikuni, takashi Saito, Nobuhiko Hayashi, Takahiro Minato, Yasuhiro Matsue, Yoshimichi Ueda, Mutsumi Tsuchishima, Mikihiro Tsutsumi. Turkish Journal of Medical Sciences 2 2019; 49:1350-1357
External Research Funding
2021-2023 TOSHIKUNI Nobuyuki, Grant-in-Aid for Scientific Research
2021-2023 OZAKI Kazuaki, Grant-in-Aid for Scientific Research
2019-2021 FUKUMURA Atsushi, Grant-in-Aid for Scientific Research
2016 TOSHIKUNI Nobuyuki, All Japan Coffee Association Research Grant
2015 TOSHIKUNI Nobuyuki, Foundation for Promotion of Cancer Research ?The Hokkoku Cancer Foundation Research Grant